Home : FAQs Email Print

Is the INFUSEĀ® Bone Graft/LT-CAGEĀ® Device the same as the natural protein found in my body?michelson=yep

Dr. Robert S. Pashman
Los Angeles, CA

The product contains a synthetic protein very similar to the proteins that bone naturally produces when healing or growing.

Dr. Jeffrey C. Wang
Los Angeles, CA

The INFUSE® Bone Graft/LT-CAGE® Device contains a replication of a morphogenetic protein that is found in your body. It is a key component to bone formation and bone healing.

Dr. Dennis G. Crandall
Mesa, AZ

The INFUSE® Bone Graft/LT-CAGE® Device contains a manufactured copy of a normal protein present in your body. The protein causes a high concentration of bone forming cells to accumulate wherever it is placed. The protein is placed on a collagen sponge to hold it in place.

Dr. Kambiz Hannani
Los Angeles, CA

The INFUSE® Bone Graft/LT-CAGE® Device contains a protein identical to one type of bone-producing protein found in the human body.

Dr. Theodore A. Belanger
Charlotte, NC

The INFUSE® Bone Graft/LT-CAGE® Device contains the same as one of the proteins found naturally in your body that stimulate bone formation. The INFUSE® Bone Graft/LT-CAGE® Device contains a purified, highly concentrated protein that is commercially available for use in spinal-fusion surgeries under certain circumstances with the LT-CAGE® Lumbar Tapered Fusion Device.

Dr. Scott H. Kitchel
Eugene, OR

The INFUSE® Bone Graft/LT-CAGE® Device contains a human protein grown from a recombinant process that is one of the proteins that stimulate bone healing and fusion. It is exactly like one of the proteins in your body that stimulates this process. The material is used with the LT-CAGE® Lumbar Tapered Fusion Device.

Dr. Jorge E. Isaza
Baton Rouge, LA

Yes, the INFUSE® Bone Graft/LT-CAGE® Device contains a protein made artificially from cells that have been genetically engineered to produce the same protein that is found in the human body.

Dr. Paul J. Slosar
Daly City, CA

The INFUSE® Bone Graft/LT-CAGE® Device contains a commercially available protein that has been purified to specifically generate bone in the immediate area that it is placed. The actual history is that 30 years ago scientists discovered that certain proteins were present in fracture/ bone healing. Scientists purified those proteins and found a number of bone morphogenetic proteins, meaning proteins that will change cells into bone producing cells. Once they identified a number of proteins, they identified the ones that worked best. Many researchers spent years and years purifying these to the point where they could reliably produce bones in humans. Then they used the current technology to take the protein and manufacture that in a commercial sense so that you have the product available today that we know as the INFUSE® Bone Graft/LT-CAGE® Device.

Important Safety Information

The commentary above recounts the experiences of these physicians. Medtronic invited them to share their stories candidly. Keep in mind that results vary; not every patient's response is the same. Talk with your doctor to learn more about any products that are mentioned above.

It is important that you discuss the potential risks, complications and benefits of spinal surgery with your doctor prior to receiving treatment, and that you rely on your doctor's judgment. Only your doctor can determine whether you are a suitable candidate for this treatment.

  • Published: July 22, 2002
  • Updated: April 19, 2010